Which of the following catalyzes the cutting of PIP2 into 2 moles of IP3 and diacylglycerol in cell signaling?
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In the intermediate steps of EM algorithm, the number of each base in each column is determined and then converted to fractions.
For the 10-residue DNA sequence example, there are _______ possible starting sites for a 20-residue-long site.
An alternative method is to produce an odds scoring matrix calculated by dividing each base frequency by the background frequency of that base.
Which of the following about MEME is untrue?
Which of the following about the Gibbs sampler is untrue?
Analysis of s for conserved blocks of sequence leads to production of the position-specific scoring matrix.
The quality and quantity of information provided by the PSSM also varies for ________ in the motif.
Two considerations arise in trying to tune the PSSM so that it adequately represents the training sequences. Which of the following is not their description?
If a good sampling of sequences is _______ the number of sequences is _________ and the motif structure is ________ it should, in principle, be possible to obtain frequencies highly representative of the same motif in other sequences also.
If the data set is _______ then unless the motif has __________ amino acids in each column, the column frequencies in the motif may not be highly representative of all other occurrences of the motif.
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