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Biotech Engineering MCQs

Q:

The genome of Hepadnavirus is _______________

A) circular dsDNA B) linear dsDNA
C) circular ssDNA D) linear ssDNA
 
Answer & Explanation Answer: A) circular dsDNA

Explanation: The genome of Hepadnavirus is a circular double-stranded DNA of the size 3.2 kilobase pairs. It consists of plus and minus strands in which plus strand is incomplete and minus strand is complete but contains discontinuity (nicks) at a unique site.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

38
Q:

The Human Spumavirus contains oncogene.

A) True B) False
 
Answer & Explanation Answer: B) False

Explanation: The Human Spumavirus is the exogenous retroviruses that do not contain oncogenes. They comprise a group of “foamy virus” that cause inapparent persistent infections but have not yet been proved to cause any disease.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

35
Q:

Which of the following causes AIDS in rhesus monkeys?

A) HIV B) Spumavirus
C) SIV D) DIV
 
Answer & Explanation Answer: C) SIV

Explanation: Simian Immunodeficiency Virus (SIV) causes AIDS in rhesus (Asian) monkeys. The SIV belongs to the lentivirus genera and may occasionally infect humans but there no indication of SIV causing disease in humans.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

33
Q:

Which of the following is the demyelination of the long motor neuron tracts in the spinal cord?

A) TSP B) ATL
C) AIDS D) Cancer
 
Answer & Explanation Answer: A) TSP

Explanation: Tropical spastic paraparesis (TSP) is progressive demyelination of the long motor neuron tracts in the spinal cord. It is also known as HTLV-1 associated myelopathy that is mainly seen in 20 to 50-year-old women.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

30
Q:

Which of the following gene activates the expression of all of its genes as well as certain cellular genes?

A) gag B) pol
C) env D) lax
 
Answer & Explanation Answer: D) lax

Explanation: Lax is the regulatory gene, present in HTLV-1, that transactivates the expression of all its genes as well as certain cellular genes. The HTLV-1 is the only human retrovirus that does not contain any oncogenes.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

25
Q:

The virions of retrovirus are ___________

A) conical B) rod-shaped
C) spherical D) rhombical
 
Answer & Explanation Answer: C) spherical

Explanation: The virions of retroviruses are spherical with 80 – 100 nm in diameter and have a unique three-layered structure. The structure is enclosed within a capsid and appears icosahedral.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

54
Q:

Who described the first human retrovirus?

A) Peyton Rous B) Bob Gallo
C) Temin D) Baltimore
 
Answer & Explanation Answer: B) Bob Gallo

Explanation: Bob Gallo and his colleagues in the year 1980 described the first human retroviruses which caused the adult T cell leukemia. Gallo was also instrumental in confirming and extending the discovery by Luc Montagnier.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

30
Q:

The virions of the Filoviridae members are composed of lipid bilayers.

A) True B) False
 
Answer & Explanation Answer: A) True

Explanation: The virions of the Filoviridae members are composed of lipid bilayers. They are very long filamentous rods or more compact convoluted forms, each composed of lipid bilayers covered with peplomers.

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Category: Biotech Engineering MCQs
Sub Category: Virology Mcqs

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